PE Anti-Human CD8a Antibody[HIT8a] (E-AB-F1271D)
| Alternate Names | CD8Leu-2Ly-2, CD8, CD8 antigen alpha po, CD8 antigen alpha polypeptide, CD8A, Leu, Leu2, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu, T-lymphocyte differentiation antigen T8/Leu-2, T8, alpha polypeptide (p32), p32 |
| Clone | |
| Leadtime | Order now, ship in 3 days |
| Background | CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck. |
| Abbre | CD8a |
| Swissprot | |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Isotype | Mouse IgG1, κ |
| Isotype Control | PE Mouse IgG1, κ Isotype Control[MOPC-21] |
| Applications |
FCM
|
| Research Areas | Immunology |
| Cellular Localization |
Membrane
|
| Form | Liquid |
| Concentration |
5 μL/Test
|
| Conjugation | PE |
| Conjugation Information | PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter). |
| Spectrum | |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration Date | 24 months |
| Shipping | Ice bag |
Note: Data for this module come from published literature that cites this product, displaying other products used together in the same research paper.
Searching publications using CD8a as the keyword shows that the gene above is closely associated with CD8a in research. Results are sorted in descending order of research relevance. (The displayed numbers represent the number of publications in which both terms co-occur.)
| Cat.No. | Product Name | Sizes |
|---|---|---|
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
| Cat.No. | Product Name | Clone No. |
|---|---|---|
| AN00882D | PE Anti-Human CD8a Antibody[RPA-T8] | RPA-T8 |
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